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Efficient mRNA-Based Genetic Engineering of Human NK Cells with High-Affinity CD16 and CCR7 Augments Rituximab-Induced ADCC against Lymphoma and Targets NK Cell Migration toward the Lymph Node-Associated Chemokine CCL19

机译：具有高亲和力CD16和CCR7的人NK细胞的基于mRNa的基因工程的增强增加了利妥昔单抗诱导的针对淋巴瘤的aDCC并且靶向NK细胞向淋巴结相关趋化因子CCL19迁移

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Mattias Carlsten; Emily Levy; Amrita Karambelkar; Linhong Li; Robert Reger; Maria Berg; Madhusudan V. Peshwa; Richard W. Childs;
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年度 2016
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1. B-NHL患者NK细胞中CD16ζ表达及利妥昔单抗与LAK细胞的联合抗瘤作用 [J] . 史艳侠, 张晓实, 夏建川, 癌症（英文版） . 2007,第008期
2. Efficient mRNA-Based Genetic Engineering of Human NK Cells with High-Affinity CD16 and CCR7 Augments Rituximab-Induced ADCC against Lymphoma and Targets NK Cell Migration toward the Lymph Node-Associated Chemokine CCL19 [J] . Mattias Carlsten, Emily Levy, Amrita Karambelkar, Frontiers in Immunology . 2016,第4期

机译：高亲和力CD16和CCR7增强人类NK细胞基于mRNA的遗传工程，增强利妥昔单抗诱导的针对淋巴瘤的ADCC，并靶向NK细胞向淋巴结相关趋化因子CCL19的迁移
3. Safety and efficacy from first-in-human immunotherapy combining NK and T cell activation with off-the-shelf high-affinity CD16 NK cell line (haNK) in patients with 2nd-line or greater metastatic triple-negative breast cancer (TNBC) [J] . Intelligence: A Multidisciplinary Journal . 2020,第期

机译：第一单免疫治疗的安全性和疗效与二线或更高转移性三重阴性乳腺癌（TNBC）的患者中与现成的高亲和力CD16 NK细胞系（HANK）组合的NK和T细胞活化。（TNBC）
4. The expression of chemokines CCL19, CCL21 and their receptor CCR7 in oral squamous cell carcinoma and its relevance to cervical lymph node metastasis [J] . Oliveira-NetoH.H., DeSouzaP.P.C., DaSilvaM.R.B., Tumour biology : . 2013,第1期

机译：趋化因子CCL19，CCL21及其受体CCR7在口腔鳞状细胞癌中的表达及其与宫颈淋巴结转移的关系
5. The functional role of the activating receptors TIM-3 and CD16 in human natural killer (NK) cell biology. [D] . Gleason, Michelle Kathleen. 2012

机译：激活受体TIM-3和CD16在人类自然杀伤（NK）细胞生物学中的功能作用。
6. Efficient mRNA-Based Genetic Engineering of Human NK Cells with High-Affinity CD16 and CCR7 Augments Rituximab-Induced ADCC against Lymphoma and Targets NK Cell Migration toward the Lymph Node-Associated Chemokine CCL19 [O] . Mattias Carlsten, Emily Levy, Amrita Karambelkar, 2016

机译：高亲和力CD16和CCR7增强人类NK细胞基于mRNA的遗传工程增强利妥昔单抗诱导的ADCC对抗淋巴瘤并靶向NK细胞向淋巴结相关趋化因子CCL19的迁移
7. Efficient mRNA-based Genetic Engineering of Human NK Cells with High-Affinity CD16 and CCR7 Augments Rituximab-induced ADCC against Lymphoma and Targets NK cell Migration Towards the Lymph Node Associated Chemokine CCL19 [O] . Mattias eCarlsten, Emily eLevy, Amrita eKarambelkar, 2016

机译：具有高亲和力CD16和CCR7的人NK细胞的基于mRNa的基因工程的增强增加利妥昔单抗诱导的针对淋巴瘤的aDCC并且靶向NK细胞向淋巴结相关的趋化因子CCL19迁移

Efficient mRNA-Based Genetic Engineering of Human NK Cells with High-Affinity CD16 and CCR7 Augments Rituximab-Induced ADCC against Lymphoma and Targets NK Cell Migration toward the Lymph Node-Associated Chemokine CCL19

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